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ABSTRACT: Background
Autonomic nervous system (ANS) dysfunction is an important factor in the development and progression of arterial hypertension (AH) and may produce adverse hemodynamic sequelae. ANS function can be evaluated by analyzing heart rate variability (HRV). The purpose of this study was to assess the possible correlation between HRV and the hemodynamic profile of AH patients, including antihypertensive treatment effects after 12 months.Methods
The study was conducted on 144 patients with uncomplicated AH. The hemodynamic profile was assessed via echocardiography and impedance cardiography (ICG). The analyzed HRV parameters included SDNN, rMSSD, pNN50, low frequency (LF, 0.05-0.15 Hz), high frequency (HF, 0.15-0.4 Hz), total power (TP, the variance of all NN intervals), and the day, night, and 24-h low-to-high frequency ratios (LF/HF).Results
Analysis showed various correlations of HRV parameters both with arterial blood pressure and with the hemodynamic profile assessed via echocardiography and ICG. The HRV parameters of increased ANS activity showed a correlation with improved left ventricle function (LV) and lower LV afterload.Conclusions
Effective antihypertensive treatment demonstrated beneficial effects on both the ANS balance and the hemodynamic profile.
SUBMITTER: Maciorowska M
PROVIDER: S-EPMC9267277 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Maciorowska Małgorzata M Krzesiński Paweł P Wierzbowski Robert R Uziębło-Życzkowska Beata B Gielerak Grzegorz G
Journal of clinical medicine 20220629 13
<h4>Background</h4>Autonomic nervous system (ANS) dysfunction is an important factor in the development and progression of arterial hypertension (AH) and may produce adverse hemodynamic sequelae. ANS function can be evaluated by analyzing heart rate variability (HRV). The purpose of this study was to assess the possible correlation between HRV and the hemodynamic profile of AH patients, including antihypertensive treatment effects after 12 months.<h4>Methods</h4>The study was conducted on 144 pa ...[more]