Remodeling of Retinal Arterioles and Carotid Arteries in Heart Failure Development-A Preliminary Study.

ABSTRACT: Current data indicate that heart failure (HF) is associated with inflammation and microvascular dysfunction and remodeling. These mechanisms could be involved in HF development and progression, especially in HF with preserved ejection fraction (HFpEF). We aimed to compare structural changes in retinal arterioles and carotid arteries between HF patients and patients without heart failure. This preliminary, retrospective, case-control study included 28 participants (14 patients with HFpEF and 14 age- and sex-matched healthy controls). Carotid intima-media thickness to lumen ratio (cIMTLR) was assessed using B-mode ultrasonography. Retinal arterioles wall- to-lumen ratio (rWLR) was assessed by adaptive optics camera rtx1. The HF patients had higher IMTLR (Δ_median [HFpEF-control gro

SUBMITTER: Sadowski J 

PROVIDER: S-EPMC9267807 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature