Bound Electron Enhanced Radiosensitisation of Nimorazole upon Charge Transfer.

ABSTRACT: This novel work reports nimorazole (NIMO) radiosensitizer reduction upon electron transfer in collisions with neutral potassium (K) atoms in the lab frame energy range of 10-400 eV. The negative ions formed in this energy range were time-of-flight mass analyzed and branching ratios were obtained. Assignment of different anions showed that more than 80% was due to the formation of the non-dissociated parent anion NIMO^•- at 226 u and nitrogen dioxide anion NO₂^- at 46 u. The rich fragmentation pattern revealed that significant collision induced the decomposition of the 4-nitroimidazole ring, as well as other complex internal reactions within the temporary negative ion formed after electron transfer to neutral NIMO. Other fragment anions were only responsible f

SUBMITTER: Kumar S 

PROVIDER: S-EPMC9268075 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature