Dataset Information

CYP7A1, NPC1L1, ABCB1, and CD36 Polymorphisms Associated with Coenzyme Q₁₀ Availability Affect the Subjective Quality of Life Score (SF-36) after Long-Term CoQ₁₀ Supplementation in Women.

ABSTRACT: The single nucleotide polymorphisms (SNPs) rs3808607, rs2072183, rs2032582, and rs1761667 are associated with coenzyme Q₁₀ (CoQ₁₀) bioavailability in women after long-term CoQ₁₀ supplementation. However, the beneficial aspects of the association between these SNPs and CoQ₁₀ supplementation remain unknown. We investigated their relationship using the subjective quality of life score SF-36 by reanalyzing previous data from 92 study participants who were receiving ubiquinol (a reduced form of CoQ₁₀) supplementation for 1 year. Two-way repeated-measures analysis of variance revealed a significant interaction between rs1761667 and the SF-36 scores of role physical (p = 0.016) and mental health (p = 0.017) in women. Subgrouping

SUBMITTER: Takahashi M

PROVIDER: S-EPMC9268390 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Dataset Information

CYP7A1, NPC1L1, ABCB1, and CD36 Polymorphisms Associated with Coenzyme Q₁₀ Availability Affect the Subjective Quality of Life Score (SF-36) after Long-Term CoQ₁₀ Supplementation in Women.

OmicsDI is part of the ELIXIR infrastructure

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Dataset Information

CYP7A1, NPC1L1, ABCB1, and CD36 Polymorphisms Associated with Coenzyme Q10 Availability Affect the Subjective Quality of Life Score (SF-36) after Long-Term CoQ10 Supplementation in Women.

OmicsDI is part of the ELIXIR infrastructure

Tweets

CYP7A1, NPC1L1, ABCB1, and CD36 Polymorphisms Associated with Coenzyme Q₁₀ Availability Affect the Subjective Quality of Life Score (SF-36) after Long-Term CoQ₁₀ Supplementation in Women.