Characterization of regional variation of bone mineral density in the geriatric human cervical spine by quantitative computed tomography.

ABSTRACT:

Background

Odontoid process fractures are among the most common in elderly cervical spines. Their treatment often requires fixation, which may include use of implants anteriorly or posteriorly. Bone density can significantly affect the outcomes of these procedures. Currently, little is known about bone mineral density (BMD) distributions within cervical spine in elderly. This study documented BMD distribution across various anatomical regions of elderly cervical vertebrae.

Methods and findings

Twenty-three human cadaveric C1-C5 spine segments (14 males and 9 female, 74±9.3 y.o.) were imaged via quantitative CT-scan. Using an established experimental protocol, the three-dimensional shapes of the vertebrae were reconstructed from CT images and partitioned in bone regions (4 re

SUBMITTER: Garay RS 

PROVIDER: S-EPMC9269429 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature