Glomerular Exostosin as a Subtype and Activity Marker of Class 5 Lupus Nephritis.

ABSTRACT:

Background and objectives

There have been only several studies on the correlation between glomerular exostosin expression and membranous lupus nephritis. In this study, we validate the previous findings in Chinese patients with class 5 lupus nephritis.

Design, setting, participants, & measure

One hundred sixty-five patients with class 5 lupus nephritis and varying numbers of control patients were included. Exostosin1/exostosin2 staining was performed by immunohistochemistry, and the staining intensity was quantified using an imaging analysis system. Between-group comparisons were tested for statistical significance using the Pearson chi-squared test, the Fisher exact test, the unpaired t test, the Mann-Whitney U test, or one-way ANOVA.

Results

In total,

SUBMITTER: Wang C 

PROVIDER: S-EPMC9269634 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature