Characterizing superspreading potential of infectious disease: Decomposition of individual transmissibility.

ABSTRACT: In the context of infectious disease transmission, high heterogeneity in individual infectiousness indicates that a few index cases can generate large numbers of secondary cases, a phenomenon commonly known as superspreading. The potential of disease superspreading can be characterized by describing the distribution of secondary cases (of each seed case) as a negative binomial (NB) distribution with the dispersion parameter, k. Based on the feature of NB distribution, there must be a proportion of individuals with individual reproduction number of almost 0, which appears restricted and unrealistic. To overcome this limitation, we generalized the compound structure of a Poisson rate and included an additional parameter, and divided the reproduction number into independent and additive fixed

SUBMITTER: Zhao S 

PROVIDER: S-EPMC9269899 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature