Optimizing acquisition times for total-body positron emission tomography/computed tomography with half-dose ¹⁸F-fluorodeoxyglucose in oncology patients.

ABSTRACT:

Background

The present study aimed to explore the boundary of acquisition time and propose an optimized acquisition time range for total-body positron emission tomography (PET)/computed tomography (CT) oncological imaging using half-dose (1.85 MBq/kg) ¹⁸F-fluorodeoxyglucose activity based on diagnostic needs.

Methods

In this retrospective study based on a total-body PET system (uEXPLORER), an exploration cohort (October 2019-December 2019) of 46 oncology patients was first studied. The acquisition time for all patients was 15 min, and the acquired images were reconstructed and further split into 15-, 8-, 5-, 3-, 2-, and 1-min duration groups (abbreviated as G15, G8, G5, G3, G2, and G1). The image quality and lesion detectability of reconstructed PET images with di

SUBMITTER: He Y 

PROVIDER: S-EPMC9270529 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature