Prognostic models for outcome prediction in patients with advanced hepatocellular carcinoma treated by systemic therapy: a systematic review and critical appraisal.

ABSTRACT:

Objective

To describe and analyze the predictive models of the prognosis of patients with hepatocellular carcinoma (HCC) undergoing systemic treatment.

Design

Systematic review.

Data sources

PubMed and Embase until December 2020 and manually searched references from eligible articles.

Eligibility criteria for study selection

The development, validation, or updating of prognostic models of patients with HCC after systemic treatment.

Results

The systematic search yielded 42 eligible articles: 28 articles described the development of 28 prognostic models of patients with HCC treated with systemic therapy, and 14 articles described the external validation of 32 existing prognostic models of patients with HCC undergoing systemic treatment. Among the 28 progno

SUBMITTER: Li L 

PROVIDER: S-EPMC9270753 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature