Interneuron control of C. elegans developmental decision-making.

ABSTRACT: Natural environments are highly dynamic, and this complexity challenges animals to accurately integrate external cues to shape their responses. Adaptive developmental plasticity enables organisms to remodel their physiology, morphology, and behavior to better suit the predicted future environment and ultimately enhance their ecological success.¹ Understanding how an animal generates a neural representation of current and forecasted environmental conditions and converts these circuit computations into a predictive adaptive physiological response may provide fundamental insights into the molecular and cellular basis of decision-making over developmentally relevant timescales. Although it is known that sensory cues usually trigger the developmental switch and that downstream inter-

SUBMITTER: Chai CM 

PROVIDER: S-EPMC9270850 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature