Stroke population-specific neuroanatomical CT-MRI brain atlas.

ABSTRACT:

Purpose

Development of a freely available stroke population-specific anatomical CT/MRI atlas with a reliable normalisation pipeline for clinical CT.

Methods

By reviewing CT scans in suspected stroke patients and filtering the AIBL MRI database, respectively, we collected 50 normal-for-age CT and MRI scans to build a standard-resolution CT template and a high-resolution MRI template. The latter was manually segmented into anatomical brain regions. We then developed and validated a MRI to CT registration pipeline to align the MRI atlas onto the CT template. Finally, we developed a CT-to-CT-normalisation pipeline and tested its reliability by calculating Dice coefficient (Dice) and Average Hausdorff Distance (AHD) for predefined areas in 100 CT scans from ischaemic stroke patie

SUBMITTER: Kaffenberger T 

PROVIDER: S-EPMC9271109 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature