Predictive performance of selected breath volatile organic carbon compounds in stage 1 lung cancer.

ABSTRACT:

Background

Lung cancer remains the leading cause of cancer deaths accounting for almost 25% of all cancer deaths. Breath-based volatile organic compounds (VOCs) have been studied in lung cancer but previous studies have numerous limitations. We conducted a prospective matched case to control study of the ability of preidentified VOC performance in the diagnosis of stage 1 lung cancer (S1LC).

Methods

Study participants were enrolled in a matched case to two controls study. A case was defined as a patient with biopsy-confirmed S1LC. Controls included a matched control, by risk factors, and a housemate control who resided in the same residence as the case. We included 88 cases, 88 risk-matched, and 49 housemate controls. Each participant exhaled into a Tedlar^® bag wh

SUBMITTER: Smirnova E 

PROVIDER: S-EPMC9271440 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature