Predictive preoperative clinical score for patients with liver-only oligometastatic colorectal cancer.

ABSTRACT:

Background

Resection of liver metastases from colorectal cancer (CRC) in the oligometastatic stage improves survival and is a potentially curative treatment. Thus, predictive scores that reliably identify those patients who especially benefit from surgery are essential.

Patients and methods

In this multicenter analysis, 512 patients had undergone surgery for liver metastases from CRC. We investigated distinct cancer-specific risk factors that are routinely available in clinical practice and developed a predictive preoperative score using a training cohort (TC), which was thereafter tested in a validation cohort (VC).

Results

Inflammatory response to the tumor, a right-sided primary tumor, multiple liver metastases, and node-positive primary tumor were significant adve

SUBMITTER: Filippini Velazquez G 

PROVIDER: S-EPMC9271475 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature