Treatment Outcomes for Osteoradionecrosis of the Central Skull Base: A Systematic Review.

ABSTRACT: Objective  Osteoradionecrosis (ORN) of the skull base can have catastrophic consequences if not detected early and managed appropriately. This is a systematic review of the different treatment modalities for skull base ORN and their outcomes. Study Design  This study is a systematic review. Materials and Methods  Two researchers extracted information including patient population, surgical technique, outcomes of interest, and study design. A computerized search of Medline, Embase, and the Cochrane library (January 1990-June 2020) looked for several papers on the subject of skull base ORN. Results  A total of 29 studies had met inclusion criteria, including data from 333 patients. Nasopharyngeal carcinoma was the most common primary tumor (85%). Average age at dia

SUBMITTER: Shaikh N 

PROVIDER: S-EPMC9272279 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature