Progression to Critical Illness and Death in Patients With Breakthrough Hospitalizations.

ABSTRACT:

Background

Characterization of disease progression and outcomes after coronavirus disease 2019 (COVID-19)-related hospitalization in vaccinated compared with unvaccinated individuals is limited.

Methods

This was a retrospective case-control study of symptomatic vaccinated (cases) and unvaccinated (controls) participants hospitalized for COVID-19 between December 30, 2020, and September 30, 2021, in Southeast Michigan. Hospitalized adult patients with lab-confirmed COVID-19 were identified through daily census report. Breakthrough infection was defined as detection of severe acute respiratory syndrome coronavirus 2 ≥14 days after completion of the primary vaccination series. The association between prior vaccination and critical COVID-19 illness (composite of intensive care u

SUBMITTER: Suleyman G 

PROVIDER: S-EPMC9272434 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature