Effects of word frequency on semantic memory in schizophrenia: electrophysiological evidence for a deficit in linguistic access.

ABSTRACT:

Background

Abnormal storage and/or access are among the hypothesized causes of semantic memory deficit in schizophrenia. Neuropsychological and connectionist models have emphasized functional systems that serve the processing of word meaning and frequency: semantic storage disturbance is presumed to result from weak representations of word meaning; defective access is assumed to result from compromises to pathways that activate word frequency knowledge. Candidate biological systems include neuromodulatory pathways that normally function to enhance neural signals (e.g., cholinergic system). Electrophysiological responding may be informative regarding the storage-access distinction for schizophrenia.

Methods

Visual event-related potentials were recorded for 14 schizophrenia ou

SUBMITTER: Condray R 

PROVIDER: S-EPMC9272462 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature