Persistent ¹²⁹Xe MRI Pulmonary and CT Vascular Abnormalities in Symptomatic Individuals with Post-acute COVID-19 Syndrome.

ABSTRACT:

Background

In patients with post-acute COVID-19 syndrome (PACS), abnormal gas-transfer and pulmonary vascular density have been reported, but such findings have not been related to each other or to symptoms and exercise limitation. The pathophysiologic drivers of PACS in patients previously infected with COVID-19 who were admitted to in-patient treatment in hospital (or ever-hospitalized patients) and never-hospitalized patients are not well understood.

Purpose

To determine the relationship of persistent symptoms and exercise limitation with xenon 129 (¹²⁹Xe) MRI and CT pulmonary vascular measurements in individuals with PACS.

Materials and methods

In this prospective study, patients with PACS aged 18-80 years with a positive polymerase chain reaction COVID

SUBMITTER: Matheson AM 

PROVIDER: S-EPMC9272782 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature