2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

ABSTRACT:

Objective

To develop updated guidelines for the pharmacologic management of rheumatoid arthritis.

Methods

We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the certainty of evidence. A voting panel comprising clinicians and patients achieved consensus on the direction (for or against) and strength (strong or conditional) of recommendations.

Results

The guideline addresses treatment with disease-modifying antirheumatic drugs (DMARDs), including conventional synthetic DMARDs, biologic DMARDs, and targeted synthetic DMARDs, use of glucocorticoids, and use of DMARDs in c

SUBMITTER: Fraenkel L 

PROVIDER: S-EPMC9273041 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature