Stepped treatment algorithm using budesonide-formoterol for chronic respiratory diseases: A single arm interventional study.

ABSTRACT:

Background

While the safety and efficacy of inhaled budesonide-formoterol, used as-needed for symptoms, has been established for patients with asthma, it has not been trialed in undifferentiated patients with chronic respiratory diseases. We aimed to assess the feasibility of a pragmatic intervention that entails a stepped algorithm using inhaled budesonide-formoterol (dry powder inhaler, 160μg/4.5μg per dose) for patients presenting with chronic respiratory diseases to three rural district hospitals in Hanoi, Vietnam.

Methods

We recruited patients with evidence of airflow obstruction on spirometry and/or symptoms consistent with asthma. The algorithm consisted of three steps: 1. as-needed inhaled budesonide-formoterol for symptoms, 2. maintenance plus as-needed inhaled bude

SUBMITTER: Huang WC 

PROVIDER: S-EPMC9273083 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature