Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group.

ABSTRACT: Observational studies suggest that nutritional factors have a potential cognitive benefit. However, systematic reviews of randomised trials of dietary and nutritional supplements have reported largely null effects on cognitive outcomes and have highlighted study inconsistencies and other limitations. In this Personal View, the Nutrition for Dementia Prevention Working Group presents what we consider to be limitations in the existing nutrition clinical trials for dementia prevention. On the basis of this evidence, we propose recommendations for incorporating dietary patterns and the use of genetic, and nutrition assessment tools, biomarkers, and novel clinical trial designs to guide future trial developments. Nutrition-based research has unique challenges that could require testing both mor

SUBMITTER: Yassine HN 

PROVIDER: S-EPMC9273104 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature