Inferring characteristics of bacterial swimming in biofilm matrix from time-lapse confocal laser scanning microscopy.

ABSTRACT: Biofilms are spatially organized communities of microorganisms embedded in a self-produced organic matrix, conferring to the population emerging properties such as an increased tolerance to the action of antimicrobials. It was shown that some bacilli were able to swim in the exogenous matrix of pathogenic biofilms and to counterbalance these properties. Swimming bacteria can deliver antimicrobial agents in situ, or potentiate the activity of antimicrobial by creating a transient vascularization network in the matrix. Hence, characterizing swimmer trajectories in the biofilm matrix is of particular interest to understand and optimize this new biocontrol strategy in particular, but also more generally to decipher ecological drivers of population spatial structure in natural biofilms ecosyste

SUBMITTER: Ravel G 

PROVIDER: S-EPMC9273218 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature