External validation and comparison of simple tools to screen for nonalcoholic fatty liver disease in Chinese community population.

ABSTRACT:

Background

Various noninvasive tools based on anthropometric indicators, blood lipids, and liver enzymes, etc. have been developed to screen for nonalcoholic fatty liver disease (NAFLD), with different diagnostic performance and cutoff values among studies. We aimed to validate and compare eight NAFLD-related models developed by simple indicators and to define their cutoff values in Chinese community population.

Methods

A cross-sectional study was conducted in a health examination cohort of 3259 people. NAFLD was diagnosed by ultrasonography. General, anthropometric and biochemical data were collected. Fatty liver index (FLI), fatty liver disease index (FLD), Zhejiang University index (ZJU), lipid accumulation product (LAP), regression formula of controlled attenuation param

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9273302 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature