Identification of Survival Risk and Immune-Related Characteristics of Kidney Renal Clear Cell Carcinoma.

ABSTRACT:

Background

Immunity exerts momentous functions in the progression and treatment of kidney renal clear cell carcinoma (KIRC). A better understanding of the relationship between KIRC and immunity may make a great contribution to evaluating the prognosis and immune-related therapeutic response of KIRC.

Methods

A series of information such as RNA sequence, clinical data, and tumor mutation burden (TMB) of KIRC patients were downloaded through The Cancer Genome Atlas (TCGA). Next, combining the survival information and gene expression data of TCGA and Gene Expression Omnibus (GEO), we established an immune gene-related prognosis model (IGRPM) and analyzed it. Then we constructed a nomogram which was convenient for clinicians to judge the prognosis of KIRC. Last but not the least,

SUBMITTER: Wu X 

PROVIDER: S-EPMC9273399 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature