Risk of myocarditis and pericarditis following BNT162b2 and mRNA-1273 COVID-19 vaccination.

ABSTRACT:

Background

Evidence indicates that mRNA COVID-19 vaccination is associated with risk of myocarditis and possibly pericarditis, especially in young males. It is not clear if risk differs between mRNA-1273 versus BNT162b2. We assessed if risk differs using comprehensive health records on a diverse population.

Methods

Members 18-39 years of age at eight integrated healthcare-delivery systems were monitored using data updated weekly and supplemented with medical record review of myocarditis and pericarditis cases. Incidence of myocarditis and pericarditis events that occurred among vaccine recipients 0 to 7 days after either dose 1 or 2 of a messenger RNA (mRNA) vaccine was compared with that of vaccinated concurrent comparators who, on the same calendar day, had received their

SUBMITTER: Goddard K 

PROVIDER: S-EPMC9273527 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature