Increased incident rates of antidepressant use during the COVID-19 pandemic: interrupted time-series analysis of a nationally representative sample.

ABSTRACT:

Background

The COVID-19 pandemic has been associated with increased levels of depression and anxiety with implications for the use of antidepressant medications.

Methods

The incident rate of antidepressant fills before and during the COVID-19 pandemic were compared using interrupted time-series analysis followed by comprehensive sensitivity analyses on data derived from electronic medical records from a large health management organization providing nationwide services to 14% of the Israeli population. The dataset covered the period from 1 January 2013 to 1 February 2021, with 1 March 2020 onwards defined as the period of the COVID-19 pandemic. Forecasting analysis was implemented to test the effect of the vaccine roll-out and easing of social restrictions on antidepressant

SUBMITTER: Frangou S 

PROVIDER: S-EPMC9273730 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature