Multivisceral Resection for Locally Advanced Gastric Cancer.

ABSTRACT:

Background

Locally advanced gastric cancer (LAGC) presents a therapeutic dilemma, particularly as it often involves adjacent organs through desmoplasia or true pathologic invasion. To obtain a margin-negative resection, these tumors require en bloc gastrectomy with multivisceral resection (G+MVR), and contention remains regarding its safety and oncologic benefit.

Methods

We used the National Cancer Database to retrospectively evaluate the short- and long-term outcomes of patients with LAGC treated in the USA between 2004 and 2016. Associations with margin status and perioperative outcomes were calculated using logistic regression. Survival was estimated using Cox proportional hazards regression and the Kaplan-Meier method.

Results

Overall, 785 pathologic stage T4b (pT

SUBMITTER: Aversa JG 

PROVIDER: S-EPMC9274296 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature