Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses.

ABSTRACT:

Objective

To investigate the effects of fever therapy compared with no fever therapy in a wide population of febrile adults.

Design

Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials.

Data sources

CENTRAL, BIOSIS, CINAHL, MEDLINE, Embase, LILACS, Scopus, and Web of Science Core Collection, searched from their inception to 2 July 2021.

Eligibility criteria

Randomised clinical trials in adults diagnosed as having fever of any origin. Included experimental interventions were any fever therapy, and the control intervention had to be no fever therapy (with or without placebo/sham).

Data extraction and synthesis

Two authors independently selected studies, extracted data, and assessed the risk of bias. Primary outco

SUBMITTER: Holgersson J 

PROVIDER: S-EPMC9274300 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature