Stimulus valence, episodic memory, and the priming of brain activation profiles in borderline personality disorder.

ABSTRACT:

Background

Borderline personality disorder (BPD) is characterized by instability in affective regulation that can result in a loss of cognitive control. Triggers may be neuronal responses to emotionally valenced context and/or stimuli. 'Neuronal priming' indexes the familiarity of stimuli, and may capture the obligatory effects of affective valence on the brain's processing system, and how such valence mediates responses to the repeated presentation of stimuli. We investigated the effects of affective valence of stimuli on neuronal priming (i.e. changes in activation to repeated presentation of stimuli), and if these effects distinguished BPD patients from controls.

Methods

Forty BPD subjects and 25 control subjects (age range: 18-44) participated in an episodic memory task

SUBMITTER: Szczepaniak M 

PROVIDER: S-EPMC9275123 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature