Associations between cancer family history and esophageal cancer and precancerous lesions in high-risk areas of China.

ABSTRACT:

Background

Family clustering of esophageal cancer (EC) has been found in high-risk areas of China. However, the relationships between cancer family history and esophageal cancer and precancerous lesions (ECPL) have not been comprehensively reported in recent years. This study aimed to provide evidence for identification of high-risk populations.

Methods

This study was conducted in five high-risk areas in China from 2017 to 2019, based on the National Cohort of Esophageal Cancer. The permanent residents aged 40 to 69 years were examined by endoscopy, and pathological examination was performed for suspicious lesions. Information on demographic characteristics, environmental factors, and cancer family history was collected. Unconditional logistic regression was applied to evalu

SUBMITTER: Zhou J 

PROVIDER: S-EPMC9276202 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature