Association between neutrophil-lymphocyte ratio and lymph node metastasis in gastric cancer: A meta-analysis.

ABSTRACT:

Introduction and aim

The prognostic role of neutrophil to lymphocyte ratio (NLR) has been explored extensively in the literature. The aim of this meta-analysis was to evaluate the link between NLR and lymph node metastasis in gastric cancer. A method for increasing specificity and sensitivity of pre-treatment staging has implications on treatment algorithms and survival.

Search strategy

The relevant databases were searched as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flowchart. After selection, 12 full text articles that met the inclusion criteria were included for quantitative analysis. 2 × 2 squares were generated using lymph node positive/negative, and NLR high/low data. The effect size for each study was calculated using the DerSimonian-L

SUBMITTER: Kotecha K 

PROVIDER: S-EPMC9276313 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature