Hemodynamic effects of different fluid volumes for a fluid challenge in septic shock patients.

ABSTRACT:

Background

It is still unclear what the minimal infusion volume is to effectively predict fluid responsiveness. This study was designed to explore the minimal infusion volume to effectively predict fluid responsiveness in septic shock patients. Hemodynamic effects of fluid administration on arterial load were observed and added values of effective arterial elastance (Ea) in fluid resuscitation were assessed.

Methods

Intensive care unit septic shock patients with indwelling pulmonary artery catheter (PAC) received five sequential intravenous boluses of 100 mL 4% gelatin. Cardiac output (CO) was measured with PAC before and after each bolus. Fluid responsiveness was defined as an increase in CO >10% after 500 mL fluid infusion.

Results

Forty-seven patients were included

SUBMITTER: Yang T 

PROVIDER: S-EPMC9276377 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature