Differential detection by breast density for digital breast tomosynthesis versus digital mammography population screening: a systematic review and meta-analysis.

ABSTRACT:

Background

We examined whether digital breast tomosynthesis (DBT) detects differentially in high- or low-density screens.

Methods

We searched six databases (2009-2020) for studies comparing DBT and digital mammography (DM), and reporting cancer detection rate (CDR) and/or recall rate by breast density. Meta-analysis was performed to pool incremental CDR and recall rate for DBT (versus DM) for high- and low-density (dichotomised based on BI-RADS) and within-study differences in incremental estimates between high- and low-density. Screening settings (European/US) were compared.

Results

Pooled within-study difference in incremental CDR for high- versus low-density was 1.0/1000 screens (95% CI: 0.3, 1.6; p = 0.003). Estimates were not significantly different in US (0.6/10

SUBMITTER: Li T 

PROVIDER: S-EPMC9276736 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature