Genome-wide signatures of synergistic epistasis during parallel adaptation in a Baltic Sea copepod.

ABSTRACT: The role of epistasis in driving adaptation has remained an unresolved problem dating back to the Evolutionary Synthesis. In particular, whether epistatic interactions among genes could promote parallel evolution remains unexplored. To address this problem, we employ an Evolve and Resequence (E&R) experiment, using the copepod Eurytemora affinis, to elucidate the evolutionary genomic response to rapid salinity decline. Rapid declines in coastal salinity at high latitudes are a predicted consequence of global climate change. Based on time-resolved pooled whole-genome sequencing, we uncover a remarkably parallel, polygenic response across ten replicate selection lines, with 79.4% of selected alleles shared between lines by the tenth generation of natural selection. Using extensive computer s

SUBMITTER: Stern DB 

PROVIDER: S-EPMC9276764 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature