Health-related quality of life, fatigue and health utilities in lupus nephritis: A systematic literature review.

ABSTRACT:

Background

Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease characterized by abnormal B-cell activation and the presence of autoantibodies, which can result in organ damage. Lupus nephritis (LN) is the most common severe organ manifestation of SLE and may result in impaired kidney function. However, there is limited research on the health-related quality of life (HRQoL) burden amongst patients with LN. The objective of this systematic literature review was to assess the HRQoL, fatigue and health utilities associated with LN.

Methods

A structured literature search (GSK Study 212980) of the MEDLINE and Embase databases was conducted in July 2019 and updated September 2021. Relevant international congress abstracts from 2016 to 2021 were searched, and gray li

SUBMITTER: Kharawala S 

PROVIDER: S-EPMC9277333 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature