The obstructive sleep apnoea syndrome in adolescents.

ABSTRACT:

Background

The obstructive sleep apnoea syndrome (OSAS) results from a combination of structural and neuromotor factors; however, the relative contributions of these factors have not been studied during the important developmental phase of adolescence. We hypothesised that adenotonsillar volume (ATV), nasopharyngeal airway volume (NPAV), upper airway critical closing pressure (Pcrit) in the hypotonic and activated neuromotor states, upper airway electromyographic response to subatmospheric pressure and the ventilatory response to CO₂ during sleep would be major predictors of OSAS risk.

Methods

42 obese adolescents with OSAS and 37 weight-matched controls underwent upper airway MRI, measurements of Pcrit, genioglossal electromyography and ventilatory response to CO

SUBMITTER: Marcus CL 

PROVIDER: S-EPMC9277419 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature