Economic Evaluation of Cost and Time Required for a Platform Trial vs Conventional Trials.

ABSTRACT:

Importance

Platform trial design allows the introduction of new interventions after the trial is initiated and offers efficiencies to clinical research. However, limited guidance exists on the economic resources required to establish and maintain platform trials.

Objective

To compare cost (US dollars) and time requirements of conducting a platform trial vs a series of conventional (nonplatform) trials using a real-life example.

Design, setting, and participants

For this economic evaluation, an online survey was administered to a group of international experts (146 participants) with publication records of platform trials to elicit their opinions on cost and time to set up and conduct platform, multigroup, and 2-group trials. Using the reported entry dates of 10 interv

SUBMITTER: Park JJH 

PROVIDER: S-EPMC9277502 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature