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ABSTRACT: Background
Histone deacetylation is one of the most important epigenetic modifications and plays diverse roles in plant development. However, the detailed functions and mechanisms of histone deacetylation in fiber development of cotton are still unclear. HDAC inhibitors (HDACi) have been commonly used to study the molecular mechanism underlying histone deacetylation or to facilitate disease therapy in humans through hindering the histone deacetylase catalytic activity. Trichostatin A (TSA)-the most widely used HDACi has been extensively employed to determine the role of histone deacetylation on different developmental stages of plants.Results
Through in vitro culture of ovules, we observed that exogenous application of TSA was able to inhibit the fiber initiation developmen
SUBMITTER: Wei Z
PROVIDER: S-EPMC9277824 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature