An ordinal severity scale for COVID-19 retrospective studies using Electronic Health Record data.

ABSTRACT:

Objectives

Although the World Health Organization (WHO) Clinical Progression Scale for COVID-19 is useful in prospective clinical trials, it cannot be effectively used with retrospective Electronic Health Record (EHR) datasets. Modifying the existing WHO Clinical Progression Scale, we developed an ordinal severity scale (OS) and assessed its usefulness in the analyses of COVID-19 patient outcomes using retrospective EHR data.

Materials and methods

An OS was developed to assign COVID-19 disease severity using the Observational Medical Outcomes Partnership common data model within the National COVID Cohort Collaborative (N3C) data enclave. We then evaluated usefulness of the developed OS using heterogenous EHR data from January 2020 to October 2021 submitted to N3C by 63 healt

SUBMITTER: Khodaverdi M 

PROVIDER: S-EPMC9278199 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature