Secondary sclerosing cholangitis following COVID-19 disease: a multicenter retrospective study.

ABSTRACT:

Background

Secondary sclerosing cholangitis (SSC) is a rare disease with poor prognosis. Cases of SSC have been reported following coronavirus disease 2019 (COVID-19), COVID-SSC.

Aims

Aim of this study was to compare COVID-SSC to SSC in critically ill patients (SSC-CIP) and to assess factors influencing transplant-free survival.

Methods

In this retrospective, multicenter study involving 127 patients with SSC from 9 tertiary care centers in Germany, COVID-SSC was compared to SSC-CIP and logistic regression analyses were performed investigating factors impacting transplant-free survival.

Results

24 patients had COVID-SSC, 77 patients SSC-CIP and 26 patients had other forms of SSC. COVID-SSC developed after a median of 91 days following COVID-19 diagnosis. All pat

SUBMITTER: Hunyady P 

PROVIDER: S-EPMC9278244 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature