Implications of the European Association of Urology Recommended Risk Assessment Algorithm for Early Prostate Cancer Detection.

ABSTRACT: The 2021 European Association of Urology recommendations for early prostate cancer detection included a risk-based algorithm. Risk assessment methods are proposed to prevent excessive use of prostate magnetic resonance imaging (MRI) and biopsy, simultaneously reducing overdiagnosis and overtreatment. However, the clinical implications of sequential use of risk assessment tests have not yet been properly assessed. We provide an appraisal of the recommended algorithm and evaluate its outcomes in a contemporary prospective study population of biopsy-naïve men. To increase the effectiveness in cases of limited MRI capacity, we show that use of the Rotterdam Prostate Cancer Risk Calculator-3 for pre-MRI risk stratification could avoid more than one-third of MRI examinations. After prostate MRI,

SUBMITTER: Israel B 

PROVIDER: S-EPMC9278493 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature