Effects of Blood Pressure According to Age on End-Stage Renal Disease Development in Patients With Diabetes: A Nationwide Population-Based Cohort Study.

ABSTRACT:

Background

Recent hypertension guidelines have recommended lower blood pressure (BP) targets in high-risk patients. However, there are no specific guidelines based on age or systolic and diastolic blood pressure (SBP and DBP, respectively). We aimed to assess the effects of age-related BP on development of end-stage renal disease (ESRD) in patients with diabetes.

Methods

A total of 2 563 870 patients with diabetes aged >20 years were selected from the Korean National Health Screening Program from 2009 to 2012 and followed up until the end of 2019. Participants were categorized into age and BP groups, and the hazard ratios for ESRD were calculated.

Results

During a median follow-up of 7.15 years, the incidence rates of ESRD increased with increasing SBP and DBP. The ha

SUBMITTER: Bae EH 

PROVIDER: S-EPMC9278717 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature