Survival of patients undergoing cardiac resynchronization therapy with or without defibrillator: the RESET-CRT project.

ABSTRACT:

Aims

Cardiac resynchronization therapy (CRT) is an established treatment for heart failure. There is contradictory evidence whether defibrillator capability improves prognosis in patients receiving CRT. We compared the survival of patients undergoing de novo implantation of a CRT with defibrillator (CRT-D) option and CRT with pacemaker (CRT-P) in a large health claims database.

Methods and results

Using health claims data of a major German statutory health insurance, we analysed patients with de novo CRT implantation from 2014 to 2019 without indication for defibrillator implantation for secondary prevention of sudden cardiac death. We performed age-adjusted Cox proportional hazard regression and entropy balancing to calculate weights to control for baseline imbalances. The

SUBMITTER: Hadwiger M 

PROVIDER: S-EPMC9279111 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature