Dynamic Changes of the Gut Microbiota in Preterm Infants With Different Gestational Age.

ABSTRACT: The gut microbiota plays a key role in the pathogenesis of diseases affecting preterm infants and gestational age is one of the important factors which affect the gut microbiota of infants. To determine the characteristics of the gut microbiota in preterm infants of different gestational ages from birth to 1 year after birth, we collected 622 fecal samples from neonates of different gestational ages at different time points after birth. According to the gestational ages, the samples were divided into four groups, extremely preterm, very preterm, moderate to late preterm, and term group. Meconium and fecal samples at day 14, 28, 120, and 365 after birth were collected. 16S rRNA sequencing was performed and the composition and structure of the gut microbiota in preterm infants of different g

SUBMITTER: Jia Q 

PROVIDER: S-EPMC9279133 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature