Dietary B group vitamin intake and the bladder cancer risk: a pooled analysis of prospective cohort studies.

ABSTRACT:

Purpose

Diet may play an essential role in the aetiology of bladder cancer (BC). The B group complex vitamins involve diverse biological functions that could be influential in cancer prevention. The aim of the present study was to investigate the association between various components of the B group vitamin complex and BC risk.

Methods

Dietary data were pooled from four cohort studies. Food item intake was converted to daily intakes of B group vitamins and pooled multivariate hazard ratios (HRs), with corresponding 95% confidence intervals (CIs), were obtained using Cox-regression models. Dose-response relationships were examined using a nonparametric test for trend.

Results

In total, 2915 BC cases and 530,012 non-cases were included in the analyses. The present study

SUBMITTER: Boot IWA 

PROVIDER: S-EPMC9279207 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature