Computed tomography angiography versus Agatston score for diagnosis of coronary artery disease in patients with stable chest pain: individual patient data meta-analysis of the international COME-CCT Consortium.

ABSTRACT:

Objectives

There is conflicting evidence about the comparative diagnostic accuracy of the Agatston score versus computed tomography angiography (CTA) in patients with suspected obstructive coronary artery disease (CAD).

Purpose

To determine whether CTA is superior to the Agatston score in the diagnosis of CAD.

Methods

In total 2452 patients with stable chest pain and a clinical indication for invasive coronary angiography (ICA) for suspected CAD were included by the Collaborative Meta-analysis of Cardiac CT (COME-CCT) Consortium. An Agatston score of > 400 was considered positive, and obstructive CAD defined as at least 50% coronary diameter stenosis on ICA was used as the reference standard.

Results

Obstructive CAD was diagnosed in 44.9% of patients (1100/2452

SUBMITTER: Wieske V 

PROVIDER: S-EPMC9279219 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature