The establishment of the gut microbiota in 1-year-aged infants: from birth to family food.

ABSTRACT:

Purpose

With the aim of characterizing the gastrointestinal (GI) microbiota and contextually determine how different prenatal, perinatal, and postnatal factors affected its composition in early childhood, infants were enrolled in a longitudinal-prospective study named "A.MA.MI." (Alimentazione MAmma e bambino nei primi MIlle giorni; NCT04122612, October 2019).

Methods

Forty-five fecal samples were collected at 12 months of infants' age, identified as the 3rd follow-up (T3). The evaluated variables were pre-gestational weight and weight gain during pregnancy, delivery mode, feeding, timing of weaning, and presence/absence of older siblings. Fecal alpha and beta-diversities were analyzed. Noteworthy, to determine the impact of the influencing factors, multivariate analyses wer

SUBMITTER: Vacca M 

PROVIDER: S-EPMC9279275 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature