Neural basis for anxiety and anxiety-related physiological responses during a driving situation: an fMRI study.

ABSTRACT: Although the exteroceptive and interoceptive prediction of a negative event increases a person's anxiety in daily life situations, the relationship between the brain mechanism of anxiety and the anxiety-related autonomic response has not been fully understood. In this functional magnetic resonance imaging (fMRI) study, we examined the neural basis of anxiety and anxiety-related autonomic responses in a daily driving situation. Participants viewed a driving video clip in the first-person perspective. During the video clip, participants were presented with a cue to indicate whether a subsequent crash could occur (attention condition) or not (safe condition). Enhanced activities in the anterior insula, bed nucleus of the stria terminalis, thalamus, and periaqueductal gray, and higher sympathe

SUBMITTER: Sasaoka T 

PROVIDER: S-EPMC9279323 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature