Ultrafast-UV laser integrating cavity device for inactivation of SARS-CoV-2 and other viruses.

ABSTRACT: Ultraviolet (UV) irradiation-based methods used for viral inactivation have provided an important avenue targeting severe acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) virus. A major problem with state-of-the-art UV inactivation technology is that it is based on UV lamps, which have limited efficiency, require high power, large doses, and long irradiation times. These drawbacks limit the use of UV lamps in air filtering systems and other applications. To address these limitations, herein we report on the fabrication of a device comprising a pulsed nanosecond 266 nm UV laser coupled to an integrating cavity (LIC) composed of a UV reflective material, polytetrafluoroethylene. Previous UV lamp inactivation cavities were based on polished walls with specular reflections, but the diffus

SUBMITTER: Ambardar S 

PROVIDER: S-EPMC9279343 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature