Does pretreatment elevated calcitonin level cause the poor prognosis in patients with medullary thyroid cancer?

ABSTRACT:

Background

Medullary thyroid carcinoma (MTC) patients have poor survival, tumor/node/metastasis (TNM) stage and biochemical prognosis are the most important factors. We investigated the clinical significance of calcitonin (Ctn) to assess the biochemical prognosis of MTC.

Methods

This retrospective observational study enrolled 77 MTC patients with complete information and primary surgery at the Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University between 2009 and 2020. Patient and MTC characteristics were recorded. All patients were divided into remission, stable, and progression according to biochemical prognosis. We analyzed the correlation between preoperative serum Ctn, TNM stage and biochemical prognosis.

Results

Elevated preoperative seru

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9279776 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature