Clinical study of poorly differentiated head and neck squamous cell carcinoma: a prospective cohort study in China.

ABSTRACT:

Background

Although poorly differentiated is rare in head and neck squamous cell carcinoma (HNSCC), its prognosis are worse with high rate of local recurrence and distant metastasis (DS). Therefore, this study hopes to carry out prospective clinical research on different treatment options for poorly differentiated patients and explore the treatment scheme more suitable for these patients.

Methods

This study is a prospective cohort study. We selected patients with poorly differentiated carcinoma in larynx or hypopharynx (stage I-IV, T1-4a, N0-2, M0). The intervention treatment methods for stage I-II patients are as follows: surgery, induction chemotherapy (IC) + surgery, surgery + adjuvant therapy; The intervention treatment methods for stage III-IV patients are as follows: s

SUBMITTER: Ding S 

PROVIDER: S-EPMC9279816 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature